How does DMT compare to LSD

Psychedelics - great differences from other drugs

Psychedelics are currently revolutionizing science. It deals with psychedelic substances from a new point of view. The healing effect on the psyche can no longer be denied. Scientists hope that psychedelics can soon be used legally and extensively for medical and psychotherapeutic purposes. Psychedelics are the key to being able to deal with emotional illnesses such as depression and anxiety where they arise, namely in the psyche. Psychedelics have the ability to work in a completely different way than drugs like cocaine, alcohol, heroin. But what makes psychedelics psychedelic? What is the difference to coke, etc.? We take a closer look at LSD, magic mushrooms and ayahuasca in comparison.

The group of psychedelics, to which mescaline also belongs, differs from other drug groups in one striking difference. The addiction factor that can actually be ascribed to any drug or medication does not occur with psychedelics. The brain reacts to the substance groups in a completely different way.
Cocaine, for example, creates euphoria in the brain, we reward and motivate our brain with it, after a certain time this cycle is strengthened and a higher dose of psychoactive substances is required in order to adapt to the subconscious level of reward and motivation. In short: addiction.
In comparison, magic mushrooms. They have the psychoactive substance psilocybin. Psilocybin appears to fundamentally change the infrastructure of the brain's prefrontal cortex. It changes how information is exchanged in this area of ​​the brain.

Image: Business Insider / Mike Nudelman


No other drug could even begin to induce or induce novel, permanent changes in behavior. Increased optimism about life is ascribed to the psychedelic experience gained on this “journey”.

Psilocybin isn't the only psychedelic drug researchers are studying for its potentially therapeutic effects. They also look at LSD (acid), DMT (ayahuasca), and more. Each drug has a different trip and onset time and varies in terms of legality around the world.

The main difference between LSD and psilocybin is that LSD is synthesized and psilocybin is naturally produced by magic mushrooms.

Ayahuasca (DMT), on the other hand, is usually consumed as a drink. It is brewed from the macerated and cooked vines of the Banisteriopsis caapi (yage) plant and the Psychotria viridis (chacruna) leaf. It is spiritual medicine in indigenous peoples of Bolivia, Colombia, Ecuador, and Peru. Ayahuasca's effects come from mixing the drug dimethyltryptamine or DMT from the chacruna plant and the MAO inhibitor from the yage plant, which allows the DMT to be absorbed into the bloodstream. In connection with the effects of DMT, near-death experiences are discussed. A comparatively short but very intense trip.

Psychedelic experiences are not only gained during the acute period of action of the substance, the brain also tugs at this innovative learning and knowledge process afterwards. Psychedelic drugs delay and alter the onset of habit formation by blocking the production of serotonin. The brain now reacts to well-known stimuli and also to something absolutely new. The thought processes and the ability to differentiate and perceive as well as the sensory sensitivity have grown beyond the known limits of normal consciousness. This creates the long-lasting therapeutic healing effect without addiction and dependency coming into play. Most psychedelics work through indole alkaloids, which are closely related to the body's own neurotransmitters.

Substances such as LSD and psilocybin enable access to the super- and subconscious mind when the conscious mind is clear. The lived experiences are saved without memory problems. The psychedelic experiences under psilocybin are very similar to synthetic LSD. Psilocybin usually causes a stable positive emotional color. Mood swings and emotional imbalances are rare, and it mitigates reliving repressed conflicts and traumatic experiences. In addition, psilocybin has fewer neurovegetative side effects and it shows a low tendency towards loss of identification. Therefore, when used in psychoanalysis and therapy, psilocybin has potent effects that help heal the psyche.

Source: BusinessInsider

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